Endocrine Abstracts

Introduction: The treatment of differentiated thyroid carcinoma exposes most patients to chronic supraphysiological doses of thyroid hormone which seems to have several negative effects for the patient. The goal of the present study was to assess the consequences of these doses on the bone mineral density (BMD).Patients and methods: We performed a cross-sectional study on 64 female patients followed up between 1972 and 2007. We registered the levothyroxi...

Background: Pituitary adenomas (PA) and pheochromocytomas/paragangliomas (PCC/PGL) are the main components of MEN1 and MEN2, respectively. Although the presence of both tumors (3P association, 3PAs) in the same patient could be as a result of coincidence, at least in some cases, a common pathogenic mechanism has been involved. Recently has been confirmed that germline mutations in genes coding succinate dehydrogenase (SDH) play a role in pituitary tumorigenesis. Furthermore, M...

Introduction: The demand of health care for people with gender incongruence (IG) has grown exponentially especially in young population. Due to this, there is a growing number of studies that show psychological conflicts and social functioning in those individuals who have not received gender-affirming treatment with medical intervention (pubertal block, hormone or surgical treatment) and social intervention. However, the data published so far do not represent the European cou...

Background and objective: Incidence of differentiated thyroid cancer (DTC) is increasing but not its mortality. Knowing recurrence factors is essential to plan its treatment. Recurrence related factors in our area were reviewed and compared with ATA risk stratification system.Patients and Methods: The Cadit-CAM study was designed to evaluate characteristics of patients diagnosed of DTC in Castilla La Mancha, a region in the central part of Spain, during ...

Background and objective: The AJCC-TNM system is optimized to predict survival in patients with cancer. Since January 2018, the new eighth edition of this staging system will be used to classify patients diagnosed of differentiated thyroid carcinoma (DTC). This study aims to compare the seventh and eighth editions of the AJCC-TNM system in a Spanish Cohort of DTC.Patients and Methods: The Cadit-CAM study was designed to evaluate characteristics of patien...

Introduction: In most patients with familial history of pheochromocytoma/paraganglioma, leads in the majorty of cases to a postive genetic testing for mutations, and what’s more in those patients with no familial antecedents, about 10–25% carry a mutation in one related gene. In these cases other aspects like, bilaterality, multiplicity or location must be taken into account.Objective: The objective of the study was to discuss the importance of...

Introduction: The NETTER 1 trial resulted in markedly longer progression-free survival (PFS), with preliminary evidence of an overall survival benefit. We report the results of PFS and safety of (177Lu)-DOTATATE in patients treated in our hospital between 2014 and 2017.Methods: Transversal and descriptive study of 22 patients with advanced, progressive, somatostatin receptor-positive tumors who had received previous treatments. All of them were treated w...

Aims: To compare the risk of adverse perinatal outcomes (APO) between pregnant women with mild gestational diabetes mellitus (GDM) by International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria without treatment versus women without GDM.Methods: A retrospective cohort study. We included pregnant women with prenatal care and delivery at our Institution. Group 1, women with mild GDM defined by one abnormal glucose value according to ...

Introduction: Obesity is a multifactorial disease in whose genetic factors are involved. The integration of this factors will allow to state personalized prevention strategies, where the constant contact with the patient will have a greater success for them to follow up recommendations. Continuous technological changes allow bigger accessibility to communication, having platforms with remote control.Objective: Assessing the effectiveness of an Intelligen...

Introduction: Prolactinomas are the most common tumors among functional pituitary adenomas and they constitute 40% of all pituitary tumors. Dopamine agonists (DA) are considered the primary treatment of prolactinoma. DA can lead to complete remission (including eradicacion of the tumor), allowing discotinuation of treatment. So far, there aren’t clinical criteria with sufficient predictive value for long-term remission.Objective: To assess the effec...